
Ion-Pair Free Oligonucleotide Analysis Using nSEC-MS
Ion-pair reagents contaminate systems and reduce sensitivity. Resolian’s nSEC-MS method characterizes oligonucleotides in 7.5 minutes without ion-pairing agents.

Ion-pair reagents contaminate systems and reduce sensitivity. Resolian’s nSEC-MS method characterizes oligonucleotides in 7.5 minutes without ion-pairing agents.

Discover how Resolian developed a validated LC-MS/MS method for semaglutide quantitation in human plasma, overcoming matrix effects and sensitivity challenges to support clinical trials.

Resolian combines the Cytek Aurora Full Spectrum Profiling platform with 25+ years of flow cytometry expertise to deliver complete immune clarity and confident, regulatory‑ready decisions for cell & gene therapy programs.

Turning Complexity into Clarity: Resolving siRNA Bioanalysis Challenges.
How Resolian helps pharma and biotech partners overcome LC-MS hurdles for oligonucleotide quantitation.

Discover how Resolian developed and validated a GMP HPLC-UV method to achieve baseline resolution of highly polar impurities.

Can sustainable solvents match traditional E&L extraction performance? Resolian evaluates green alternatives that equal or exceed dichloromethane recovery.
Chief Scientific Officer
Zhiyang Zhao, Ph.D., serves as Chief Scientific Officer (CSO) at Resolian. Dr. Zhao has over 30 years of pharmaceutical industry experience with special focus on drug metabolism and bioanalysis of small and large molecules in drug discovery and development. Dr. Zhao has previously held positions at Pfizer, GlaxoSmithKline, and Amgen. Before joining Resolian in 2015, Dr. Zhao served as Site Director of Preclinical Research at Amgen in Cambridge, Massachusetts, for over a decade.
Currently, Dr. Zhao serves as an Adjunct Professor at the Eshelman School of Pharmacy of the University of North Carolina at Chapel Hill, North Carolina, and as Editor-in-Chief of Drug Metabolism & Bioanalysis Letters, a journal by Bentham Science, which publishes in all areas of drug metabolism and bioanalysis. Dr. Zhao received his Ph.D. degree in Medicinal Chemistry from Virginia Polytechnic and State University (popularly known as Virginia Tech) in Blacksburg, Virginia.
Chief Executive Officer
Patrick Bennett has over 35 years of experience in pharmaceutical analysis and laboratory management. Now Chief Business Officer at Resolian, Patrick’s experience includes the roles of Strategic Marketing Director for Pharma with Thermo Fisher Scientific, LabCorp, and Vice President of Strategy and Development with PPD.
Patrick earned a B.S. degree in Toxicology and a M.S. degree in Pharmacology from the College of Pharmacy and Allied Health at St. John’s University and an M.B.A in International Marketing from the Martin J. Whitman School of Management at Syracuse University.