Validation of an LC-MS/MS Method for Simultaneous Quantification ofVenlafaxine and Its Five Metabolites in Rat Plasma and Its Application in aPharmacokinetic Study.

Determination of Venlafaxine and Five Metabolites in Rat Plasma.

The method was validated by following the US FDA guidance for bioanalytical method validation.  Click the link below to view PDF.

JCB_Apr2018_Venlafaxine in Rat Plasma Validation and PK application  

Journal of Chromatography B 1087–1088 (2018) 29–35