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> Alliance Pharma New Hire

Oct 9, 2018 10:19:28 AM / by Karen Pryor posted in Pharmaceuticals, Leadership, Philadelphia, bioanalytical, laboratory, Employee engagement, Bioanalysis, Growth, New Hire




Dr. RyanKleinAlliance Pharma has hired Dr. Ryan Klein as Director of Business Development. Dr. Klein has more than 20 years of experience in the pharmaceutical industry developing both oral and topical dosage forms for a range of indications. Dr. Klein began his career at GlaxoSmithKline, where he was an integral component of their drug discovery organization providing drug metabolism and pharmacokinetic expertise to project teams. He was instrumental in the development and implementation of a number of in vitro and in situ ADME models to assess drug absorption, metabolism, and disposition.

After leaving GSK, Dr. Klein joined Tergus Pharma, a CRO providing topical R&D services to the pharmaceutical industry. At Tergus, Ryan filled various roles including leadership positions as the Head of Research & Development and Head of In Vitro Sciences, as the company grew from five employees to approximately seventy five over a seven year period.

Dr. Klein’s areas of expertise include drug permeability, absorption and metabolism in the gastrointestinal tract, liver and skin, intestinal drug transporters, and the anatomy, physiology, and pharmacology of the skin and GI tract. He also has a strong analytical background with extensive experience developing and validating in vitro release testing methods for semi-solid dosage forms, as well as developing and validating HPLC assay and impurities methods.

Leveraging Dr. Klein’s experience on the client side allows Alliance Pharma to collaborate on a higher level with Sponsors, using his in-depth knowledge and vast experience to align the best team of scientists to support each project.

Ryan earned his bachelor’s degree in Chemistry from Wake Forest University in Winston-Salem, North Carolina, and earned his doctoral degree in Pharmaceutical Sciences from the School of Pharmacy at the University of North Carolina at Chapel Hill. Ryan has authored & co-authored numerous scientific publications and patents, and serves as a member of several pharmaceutical research focus and discussion groups.

To read more or to connect with Ryan, view his LinkedIn profile

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AAPS Distinguished Service Award to Masood Khan

May 17, 2016 5:11:00 AM / by adminweb_1 posted in Leadership


masood khan AAPS awardAlliance Pharma’s Vice President of Biopharma Services, Masood Khan, Ph.D., was honored with the BIOTEC Section Distinguished Service Award at the 2016 National Biotechnology Conference of the American Association of Pharmaceutical Scientists (AAPS). The AAPS Distinguished Service Award recognizes exemplary service as reflected in significant and extensive contributions that have materially influenced the advancement of the pharmaceutical sciences and the AAPS.

To date, Dr. Khan has over 120 publications and presentations, including several white papers related to issues in bioanalysis that focus on new technologies and biomarkers. One of these white papers titled, “Recommendations for adaptation and validation of commercial kits for biomarker quantification in drug development,” which was published in the journal of Bioanalysis (January 2015), offered a systematic approach to the assessment, method adaptation, and validation of commercial immunoassay kits for the quantification of biomarkers in drug development. Dr. Khan is also editor of a book titled, Ligand-Binding Assays: Development, Validation, and Implementation in the Drug Development Arena (2009)—a consolidated and comprehensive reference that is still used extensively in the pharmaceutical industry.

Dr. Khan has been an extraordinary volunteer, actively involved in AAPS over the past two decades, serving on a variety of committees, as well as organizing scientific short courses, roundtables, and symposia. Most notable is a roundtable that he organized at the AAPS 1998 Annual Meeting in San Francisco on the challenges of immunoassay validation and implementation in regulatory environment. This led to the publication of the first white paper on the industry perspectives on ligand-binding assay validation in 2000 and subsequently to the formation of the Ligand-Binding Assay Bioanalytical Focus Group (LBABFG), where he has actively served on the Steering Committee for over 8 years. He is currently acting as the Liaison of the BIOTEC Section Focus Groups.

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Zhiyang Zhao, Chief Scientific Officer

Sep 15, 2015 5:26:00 AM / by adminweb_1 posted in Leadership

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Alliance Pharma is pleased to announce that Zhiyang Zhao, PhD, has joined its leadership team as Chief Scientific Officer (CSO).

zhiyang zhao, chief scientific officer, alliance pharma

Dr. Zhao brings to Alliance Pharma over 20 years of pharmaceutical industry experience with special focus on metabolic and pharmacokinetic properties of small and large molecules in drug discovery and development. Dr. Zhao has previously held positions at Pfizer, GlaxoSmithKline, and Amgen. Most recently, Dr. Zhao served as Amgen’s Site Director for Preclinical Studies at Cambridge, Massachusetts, for over 11 years. He previously served as a Director at GlaxoSmithKline and as an Investigator at Pfizer. His extensive experience spans the entire drug discovery and development process (discovery, development, and in-/out-licensing) in oncology, metabolic, antiviral, CNS, and inflammatory diseases.

Dr. Zhao’s contributions and accomplishments of integrating in vitro and in vivo ADMET (absorption, distribution, metabolism, excretion, and toxicity) information to optimize drug candidate properties are documented in over 50 peer-reviewed scientific publications and patents in the areas of new drug targets, drug metabolism, pharmacokinetics, and toxicology. He currently also holds an appointment as Adjunct Professor at the Eshelman School of Pharmacy at the University of North Carolina at Chapel Hill, North Carolina, and serves as the Editor-In-Chief for Drug Metabolism Letters.

“We are thrilled to have Dr. Zhao on our scientific leadership team; he will further strengthen and broaden our scientific excellence in the services that we provide,” said Frank Li, PhD, Co founder and President of Alliance Pharma. “In his role as CSO, Dr. Zhao, will provide scientific, intellectual, and managerial leadership as well as explore scientific and business opportunities beyond Alliance Pharma’s current scope of business.”

Dr. Zhao expressed his excitement in joining the diverse team at Alliance Pharma, stating, “I look forward to working with the talented team at Alliance Pharma as we explore new business opportunities and expand our scientific and technical capabilities to better serve our clients. Having spent more than two decades in various leadership roles in pharmaceutical companies, I fully understand our clients’ challenges and needs.”

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